Analysis by American IVF experts:How to classify embryo grades？

We often hear a noun“Embryo grade”As a test tube baby,such as5AA、5AB、4ABGrade embryo,So how to divide embryo levels,This number“5”、4”What does this mean,What is a high-quality embryo。next,American IVF experts will analyze embryo grading and classification methods in detail,And take you to explore its mysteries。

What is the embryo grade?How to divide?

United StatesHRCReproductive experts say,Embryo grading is mainly achieved by observing the speed of embryo development、Divided by the morphology of blastomeres in embryos and the number of embryonic fragments。This is an important criterion for embryology experts to evaluate embryo quality from the surface and preliminarily screen high-quality embryos through morphological scoring。

The standard for embryo grading is based on the size of the blastocyst cavity by experts、Whether to incubate or not、The number and arrangement structure of inner cells and nourishing cells,Divide the development of blastocysts into six stages,for example:

Phase One:Early blastocysts with cavities,Less than the total volume of the embryo1/2;

Second phase:The volume of the blastocyst cavity is greater than or equal to the total volume of the embryo1/2;

Third stage:Complete expansion of blastocyst,The blastocyst cavity completely occupies the total volume of the embryo；

Phase Four:Expand blastocyst,At this point, the sac is completely filled with the embryo,Increase the total volume,Thin transparent tape；

Fifth issue:The hatched blastocyst partially escapes from the zona pellucida；Sixth issue:All hatched blastocysts escape from the zona pellucida。

therefore,5、This number represents the first stage of the embryo,Then the experts will discuss3-6Quality grading of inner cell clusters and trophoblast cells in stage embryos,as:

Classification of inner cell clusters:Alevel:Large number of cells,Closely arranged；Blevel；:Large number of cells；Loose arrangement；Clevel；:The number of cells is very small。

Classification of trophoblast cells:Alevel:The epithelial cell layer is composed of more cells,Dense structure；Blevel:The epithelial cell layer is composed of loosely structured small cells；Clevel:Epithelial cells are composed of sparse cells。

Through the above combination,You can know the shape of the blastocyst,as:

5AA:The inner cell mass and nourishing outer embryonic layer are both excellent high-grade blastocysts,Hatching has already begun；

5BB:The core cells of the blastocyst are abundant but not tightly packed enough,There are fewer trophoblast cells；

4AA:Tight arrangement of blastocysts,Almost no fragments,It hasn't hatched yet。

among,5AABelonging to high-quality embryos,because5AAThe embryonic cells have begun to hatch,Its quality、vitality、The implantation ability and developmental potential are more advantageous than other embryos。therefore,The higher the embryonic level,The better the quality, the better。

【Knowledge Expansion】:

Many friends ask:The higher the success rate of embryo horizontal transfer,otherwise,The two are not proportional,Because the embryo level is only a preliminary evaluation of embryo quality,Cannot detect embryonic genetic material,If the embryo has chromosomal abnormalities,So the implantation rate after transplantation will be affected,Even if the transplantation is successful, fetal miscarriage may still occur,So the higher the embryo level,The higher the success rate of test tube。

in the U.S.,In vitro fertilizationHRCExperts will use third-generation IVF technology to perform genetic testing on blastocysts,Then select healthy and high-end blastocysts for transplantation,Greatly improve the success rate of test tube and eugenics rate,Help healthy children conceive。

Three important guarantees for high success rate of IVF in the United States

in the U.S.,In vitro fertilizationHRCReproductive experts will customize personalized in vitro fertilization cycle plans based on the actual physical condition of clients,Then use advanced in vitro fertilization technology to help conceive,Avoiding pregnancy risks,Improve success rate,Helping to successfully fulfill the wish of having a child!

nowadays,The average success rate of in vitro fertilization in the United States exceeds8%,Mainly due to advanced technology、Support and guarantee from high-end medical facilities and senior reproductive experts。

【Advanced test tube technology】:in the U.S.HRCReproductive Hospital,Experts have mastered ovulation induction、Sperm washing、Single sperm injection、Advanced in vitro techniques such as blastocyst culture and genetic testing。If it can help obtain healthy blastocysts,Improve transplant success rate and eugenics rate。

【Advanced Laboratory】in the U.S.HRCThe reproductive hospital has advanced embryo laboratories(Already passedCLIAandCAPDual level certification),Because the laboratory is equipped with high-end advanced equipment and instruments,Including microscope operator、Embryo culture incubator、Spindle observation system、Laser film breaking instrument、PHMeasuring instrument、ICSIequipment、Incubator、Air purification system, etc。According to experts,Embryo culture incubator simulates the uterine environment of women,Can keep the embryo in temperature and humidity、oxygen content、Growing and developing in an environment similar to that of the female uterus, such as acidity and alkalinity,Assist in obtaining high-quality blastocysts,Establishing a solid foundation for the IVF cycle。

【Senior reproductive expert】United StatesHRCReproductive hospitals are not only large in scale,Complete and high-end medical equipment,Exquisite technical skills,Also possessing13An internationally renowned reproductive expert。Engaged in the assisted reproductive industry for decades,Superior medical skills,Rich clinical practice experience,Can provide customers with high-quality and advanced reproductive diagnosis and treatment services,Helping couples with fertility needs successfully obtain healthy children,Realize a complete and happy family。